It starts in Christchurch as the Crusaders host the Melbourne Rebels before the NSW Waratahs take on the Chiefs in Sydney.
Saturday's quad-header begins with a match-up of the Pacific sides as Fijian Drua and Moana Pasifika head to Lautoka, followed by the ladder-leading Hurricanes facing the ACT Brumbies in Canberra.
The Highlanders will look to rebound against the Western Force whilst the Queensland Reds host the Blues in Brisbane.
ROUND TEN TEAMS
*All times local
CRUSADERS v MELBOURNE REBELS
Friday April 26: Apollo Projects Stadium, Christchurch (19:05)
CRUSADERS (1-15): George Bower, Brodie McAlister, Fletcher Newell, Scott Barrett, Quinten Strange, Cullen Grace, Ethan Blackadder, Christian Lio-Willie, Mitch Drummond, Rivez Reihana, Heremaia Murray, Dallas McLeod, Levi Aumua, Sevu Reece, Johnny McNicholl
RESERVES: George Bell, Joe Moody, Owen Franks, Jamie Hannah, Corey Kellow, Noah Hotham, David Havili, Chay Fihaki
REBELS (1-15): Matt Gibbon, Alex Mafi, Sam Talakai (c), Tuaina Taii Tualima, Josh Canham, Josh Kemeny, Maciu Nabolakasi, Vaiolini Ekuasi, Ryan Louwrens, Carter Gordon, Darby Lancaster, David Feliuai, Filipo Daugunu, Lachie Anderson, Andrew Kellaway
RESERVES: Jordan Uelese, Isaac Kailea, Taniela Tupou, Angelo Smith, Rob Leota, Jack Maunder, Matt Proctor, Nick Jooste
Referee: Angus Mabey
Assistant Referees: Nick Hogan, Anthony Petrie
Key match-up: Sevu Reece vs Rebels speedster Darby Lancaster will be worth the price of admission alone.
NZR+ Expert Tipsters call: Crusaders by 20.
Think you know more than our expert? Make your predictions on each clash with the NZR+ Play Predictor HERE.
NSW WARATAHS v CHIEFS
Friday 26 April: Allianz Stadium, Sydney (19:35)
WARATAHS (1-15): Hayden Thompson-Stringer, Julian Heaven, Harry Johnson-Holmes, Hugh Sinclair, Miles Amatosero, Lachlan Swinton, Charlie Gamble, Ned Hanigan, Jake Gordon (c), Tane Edmed, Triston Reilly, Lalakai Foketi, Joey Walton, Mark Nawaqanitawase, Max Jorgensen
RESERVES: Jay Fonokalafi, Lewis Ponini, Tom Ross, Jed Holloway, Langi Gleeson, Jack Grant, Will Harrison, Izaia Perese
CHIEFS (1-15): Aidan Ross, Samisoni Taukei'aho, George Dyer, Jimmy Tupou, Tupou Vaa'i, Samipeni Finau, Kalyum Boshier (c), Wallace Sititi, Cortez Ratima, Damian McKenzie, Etene Nanai-Seturo, Rameka Pohipi, Anton Lienert-Brown, Emoni Narawa, Shaun Stevenson
RESERVES: Tyrone Thompson, Jared Proffit, Reuben O'Neill, Manaaki Selby-Rickit, Simon Parker, Xavier Roe, Josh Ioane, Quinn Tupaea
Referee: Jordan Way
Assistant Referees: Reuben Keane, Matt Kellahan
Key match-up: Damian McKenzie against Tane Edmed at first five-eighth is one of the head-to-head clashes of the season. The superstar against the rising star.
NZR+ Expert Tipsters call: Chiefs by 6.
Think you know more than our expert? Make your predictions on each clash with the NZR+ Play Predictor HERE.
FIJIAN DRUA v MOANA PASIFIKA
Saturday 27 April: Churchill Park, Lautoka (14:05)
FIJIAN DRUA (1-15): Haereiti Hetet, Zuriel Togiatama, Mesake Doge, Isoa Nasilasila, Leone Rotuisolia, Etonia Waga, Kitione Salawa, Meli Derenalagi (c), Peni Matawalu, Isaiah Armstrong-Ravula, Taniela Rakuro, Apisalome Vota, Iosefo Masi, Selestino Ravutaumada, Ilaisa Droasese
RESERVES: Mesu Dolokoto, Livai Natave, Samu Tawake, Mesake Vocevoce, Vilive Miramira, Elia Canakaivata, Simione Kuruvoli, Michael Naitokani
MOANA PASIFIKA (1-15): Abraham Pole, Samiuela Moli, Sione Mafileo, Tom Savage, Allan Craig, Irie Papuni, Jacob Norris, Sione Havili Talitui (c), Ereatara Enari, William Havili, Fine Inisi, Julian Savea, Henry Taefu. Viliami Fine, Danny Toala
RESERVES: Sama Malolo, Sateki Latu, Sekope Kepu, Ola Tauelangi, Lotu Inisi, Jonathan Taumateine, Christian Lealiifano, Neria Fomai
Referee: Graham Cooper
Assistant Referees: George Myers, James Palmer
Key match-up: With an expansive game always expected between these two sides, expect fullbacks Ilaisa Droasese and Danny Toala to spark things from open space at every opportunity.
NZR+ Expert Tipsters call: Fijian Drua by 7.
Think you know more than our expert? Make your predictions on each clash with the NZR+ Play Predictor HERE.
ACT BRUMBIES v HURRICANES
Saturday 27 April: GIO Stadium, Canberra (14:35)
BRUMBIES (1-15): James Slipper, Billy Pollard, Allan Alaalatoa, Darcy Swain, Cadeyrn Neville, Rob Valetini, Rory Scott, Charlie Cale, Ryan Lonergan (c), Noah Lolesio, Corey Toole, Tamati Tua, Len Ikitau, Ollie Sapsford, Tom Wright
RESERVES: Connal McInerney, Blake Schoupp, Sefo Kautai, Tom Hooper, Jahrome Brown, Harrison Goddard, Jack Debreczeni, Andy Muirhead
HURRICANES (1-15): Xavier Numia, James O'Reilly, Tyrel Lomax, Caleb Delany, Isaia Walker-Leawere, Brad Shields (c), Du'Plessis Kirifi, Brayden Iose, TJ Perenara, Brett Cameron, Salesi Rayasi, Jordie Barrett, Peter Umaga-Jensen, Kini Naholo, Ruben Love
RESERVES: Raymond Tuputupu, Tevita Mafileo, Pasilio Tosi, Ben Grant, Peter Lakai, Richard Judd, Riley Higgins, Bailyn Sullivan
Referee: Angus Gardner
Assistant Referees: Damon Murphy, Jeremy Markey
Key match-up: The midfield rumble between Brumbies powerhouse Len Ikitau and Hurricanes dynamo Peter Umaga-Jensen will be explosive.
NZR+ Expert Tipsters call: Brumbies by 1.
Think you know more than our expert? Make your predictions on each clash with the NZR+ Play Predictor HERE.
HIGHLANDERS v WESTERN FORCE
Saturday 27 April: Forsyth Barr Stadium, Dunedin (19:05)
HIGHLANDERS (1-15): Ethan de Groot, Henry Bell, Saula Ma'u, Mitch Dunshea, Fabian Holland, Oliver Haig, Sean Withy, Billy Harmon (c), Folau Fakatava, Rhys Patchell, Connor Garden-Bachop, Jake Te Hiwi, Tanielu Tele'a, Timoci Tavatavanawai, Jacob Ratumaitavuki-Kneepkens
RESERVES: Jack Taylor, Daniel Lienert-Brown, Jermaine Ainsley, Will Tucker, Hugh Renton, James Arscott, Cameron Millar, Martin Bogodo
FORCE (1-15): Marley Pearce, Tom Horton, Santiago Medrano, Sam Carter, Izack Rodda, Will Harris, Carlo Tizzano, Reed Prinsep, Nic White (c), Ben Donaldson, Chase Tiatia, Hamish Stewart, Sam Spink, Bayley Kuenzle, Kurtley Beale
RESERVES: Feleti Kaitu’u, Josh Bartlett, Tiaan Tauakipulu, Jeremy Williams, Michael Wells, Issak Fines-Leleiwasa, Max Burey, Henry O’Donnell
Referee: Dan Waenga
Assistant Referees: Paul Williams, Mike Winter
Key match-up: Izack Rodda was a tower of strength on return to the Force last week. This week he tussles with the Highlanders promising star Fabian Holland.
NZR+ Expert Tipsters call: Highlanders by 2.
Think you know more than our expert? Make your predictions on each clash with the NZR+ Play Predictor HERE.
QUEENSLAND REDS v BLUES
Saturday 27 April: Suncorp Stadium, Brisbane (19:35)
REDS (1-15): Alex Hodgman, Matt Faessler, Jeffery Toomaga-Allen, Ryan Smith, Angus Blyth, Liam Wright (c), John Bryant, Harry Wilson, Kalani Thomas, Tom Lynagh, Tim Ryan, Hunter Paisami, Josh Flook Suli Vunivalu, Jock Campbell
RESERVES: Josh Nasser, Peni Ravai, Sef Fa'agase, Connor Vest, Joe Brial, Louis Werchon, Lawson Creighton, Floyd Aubrey
BLUES (1-15): Ofa Tu'ungafasi, Soane Vikena, Angus Ta'avao, Patrick Tuipulotu (c), Sam Darry, Anton Segner, Dalton Papali'i, Hoskins Sotutu, Taufa Funaki, Harry Plummer, Mark Tele'a, Bryce Heem, Rieko Ioane, AJ Lam, Cole Forbes
RESERVES: Kurt Eklund, Joshua Fusitu'a, Marcel Renata, Laghlan McWhannell, James Thompson, Sam Nock, Corey Evans, Caleb Clarke
Referee: James Doleman
Assistant Referees: Jono Bredin, Fraser Hannon
Key match-up: Matt Faessler has been an absolute revelation for the Reds. He comes up against the uncompromising Kurt Eklund in an intriguing clash in the two jersey.
NZR+ Expert Tipsters call: Blues by 16
Think you know more than our expert? Make your predictions on each clash with the NZR+ Play Predictor HERE.